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Cancer: Squamous Cell Carcinoma

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Total 20315 results found since Jan 2013.

Immunohistochemical expression of endoglin (CD105) and von Willebrand factor in oral squamous cell carcinoma and its relationship with clinicopathological parameters
Conclusions The findings of this study suggest that vascular remodeling is involved in oral carcinogenesis, although there was no evidence of a significant association with clinical stage of lesions.
Source: Jornal Vascular Brasileiro - May 6, 2016 Category: Surgery Source Type: research

The interplay of matrix metalloproteinase-8, transforming growth factor- β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma
The interplay of matrix metalloproteinase-8, transforming growth factor-β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma British Journal of Cancer 117, 1007 (26 September 2017). doi:10.1038/bjc.2017.249 Authors: Pirjo Åström, Krista Juurikka, Elin S Hadler-Olsen, Gunbjørg Svineng, Nilva K Cervigne, Ricardo D Coletta, Juha Risteli, Joonas H Kauppila, Sini Skarp, Samuel Kuttner, Ana Oteiza, Meeri Sutinen & Tuula Salo
Source: British Journal of Cancer - September 26, 2017 Category: Cancer & Oncology Authors: Pirjo Åström Krista Juurikka Elin S Hadler-Olsen Gunbj ørg Svineng Nilva K Cervigne Ricardo D Coletta Juha Risteli Joonas H Kauppila Sini Skarp Samuel Kuttner Ana Oteiza Meeri Sutinen Tuula Salo Tags: matrix metalloproteinase-8 invasion proteinase web transforming growth factor- β1 vascular endothelial growth factor-C squamous cell carcinoma tongue neoplasms Source Type: research

Influence of interleukins on prognosis of patients with oral squamous cells carcinoma
ABSTRACT Squamous cell carcinoma is a malignant neoplasm that affects the structures and tissues of the oral cavity. Interleukins (IL) synthesized from a tumor modulate a cascade reaction that may influence the prognosis of the disease. We aim to investigate in the literature whether interleukins are mediators that negatively or positively influence the prognosis of patients with oral squamous cell carcinoma. A systematic review study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) instructions. PubMed (including MedLine), Scopus, Web of Science, SciELO and Latin A...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - November 11, 2019 Category: Pathology Source Type: research

Vascular and Neural Invasion in Oral Squamous Cell Carcinoma: A Study in an Iranian Population
CONCLUSION: The relation between neural and vascular invasion in OSCC with tumor's location was statistically significant. Lip and tongue carcinoma had shown more neurovascular invasion without relation to gender, age, and cell differentiation.PMID:37200766 | PMC:PMC10186046 | DOI:10.4103/abr.abr_220_21
Source: Cell Research - May 18, 2023 Category: Cytology Authors: Nakisa Torabinia Gholamreza Jahanshahi Vahid Eslami Forooz Keshani Source Type: research

In vitro study of normoxic epidermal growth factor receptor–induced hypoxia‐inducible factor‐1‐alpha, vascular endothelial growth factor, and BNIP3 expression in head and neck squamous cell carcinoma cell lines: Implications for anti–epidermal growth factor receptor therapy
ConclusionThe search for molecular predictors of sensitivity to gefitinib in HNSCC should be extended to the activation status of EGFR‐downstream pathways, phosphorylated protein kinase B, pMAPK, and HIF‐1α. © 2014 Wiley Periodicals, Inc. Head Neck, 2014
Source: Head and Neck - July 7, 2014 Category: ENT & OMF Authors: Pablo Secades, Inés Saenz Santa‐María, Anna Merlo, Carlos Suarez, María‐Dolores Chiara Tags: Original Article Source Type: research

SET8 ,a novel regulator to ameliorate vascular calcification via activating PI3K/Akt mediated anti-apoptotic effects
Biochem Cell Biol. 2021 Nov 30. doi: 10.1139/bcb-2021-0322. Online ahead of print.ABSTRACTPrevious studies have showed that the apoptosis of vascular smooth muscle cells (VSMCs) underlies the mechanism of pathological calcifications in patients with chronic kidney disease (CKD). SET domain-containing protein 8 (SET8), as an efficient protein has been reported to modulate cell apoptosis in hepatocellular carcinoma cell, esophageal squamous cell and neuronal cell through regulating pathological processes, such as cell-cycle progression and transcription regulation. However, whether SET8 is involved in high phosphorus induced...
Source: Biochemistry and Cell Biology - November 30, 2021 Category: Biochemistry Authors: Ya Ling Bai Mei Juan Cheng Jing Jing Jin Hui Ran Zhang Lei He Wei Zhou Sheng Lei Zhang Jin Sheng Xu Source Type: research

Vascular Endothelial Growth Factor A (VEGF-A) and Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) as Potential Biomarkers for Oral Squamous Cell Carcinoma: A Sri Lankan Study
CONCLUSIONS: VEGF-A gene expression, serum levels, and tissue VEGFR-2 levels correlated linearly with the stage and grade of the tumor. This study justifies the value of VEGF-A as a potential biomarker in OSCC in early detection of OSCC. More studies are needed to accept the use of VEGF-A.PMID:36708576 | DOI:10.31557/APJCP.2023.24.1.267
Source: Cancer Control - January 28, 2023 Category: Cancer & Oncology Authors: Sajith Tilal Edirisinghe Manjula Weerasekera Dulmini Kavindya De Silva Movini Thisara Devmini Shanaka Pathmaperuma Gayan Kanchana Wijesinghe Thilini Nisansala Anuradha Maddumage Haizal Huzaini Alison M Rich Harsha De Silva Milne Trudy Renuka Goonasinghe K Source Type: research

Galectin-1 induces vascular permeability through the neuropilin-1/vascular endothelial growth factor receptor-1 complex
In conclusion, our results demonstrate a novel function of Gal-1 of increasing vascular permeability through the NRP-1/VEGFR1 and Akt signaling pathway and indicate that targeting Gal-1 by an anti-Gal-1 antibody is a feasible therapy for vascular hyperpermeability and cancer.
Source: Angiogenesis - September 26, 2014 Category: Molecular Biology Source Type: research

Vascular Malformations That Were Diagnosed as or Accompanied by Malignant Tumors
CONCLUSION: When treating vascular malformations, it is advisable to be aware of the possibility of malignancy.
Source: Dermatologic Surgery - October 27, 2014 Category: Dermatology Tags: Original Article Source Type: research

Tissue expression, serum and salivary levels of vascular endothelial growth factor in patients with HNSCC
Conclusion Overexpression of vascular endothelial growth factor was found in head and neck squamous cell carcinoma patients, suggesting its role in the pathogenesis of head and neck squamous cell carcinoma, but no relation was found between tissue expression, serum levels, and salivary levels of this marker.
Source: Brazilian Journal of Otorhinolaryngology - December 11, 2014 Category: ENT & OMF Source Type: research

Vascular Invasion Predicts Recurrence in Stage IA2-IB Lung Adenocarcinoma but not Squamous Cell Carcinoma
CONCLUSION: Vascular invasion is a strong predictor of recurrence in stage IA2-IB LUAD but not in LUSC. Adjuvant therapy trials should be directed at this subgroup.PMID:36631388 | DOI:10.1016/j.cllc.2022.12.006
Source: Clinical Lung Cancer - January 11, 2023 Category: Cancer & Oncology Authors: Lubna Suaiti Travis B Sullivan Kimberly M Rieger-Christ Elliot L Servais Kei Suzuki Eric J Burks Source Type: research